Purtscher-like retinopathy in a patient with Adult-onset Still's disease and concurrent thrombotic thrombocytopenic purpura

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Case of juvenile dermatomyositis (JDM), thrombotic thrombocytopenic purpura (TTP), and Purtscher retinopathy

Methods Here we describe a previously healthy and athletic 12 year old female who was diagnosed with JDM following a period of two weeks of pruritic rash, fever, headaches, muscle pain and weakness. Her work-up was significant for elevated muscle enzymes and an abnormal MRI of bilateral quadriceps that demonstrated increased signal intensity. The patient was hospitalized for intravenous pulse m...

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difficult management of coronary artery disease in a patient with thrombotic thrombocytopenic purpura

thrombotic thrombocytopenic purpura (ttp) is a rare syndrome affecting multiple organs. there is no sufficient evidence regarding the clinical cardiac manifestations of ttp. nonetheless, pathologic cardiac involvement is quite frequent in acute ttp, which is predominantly manifested as myocardial necrosis due to coronary arteriolar microthrombosis. the present case report describes a 43-year-ol...

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Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment

Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review ...

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Retinopathy in a patient with thrombotic thrombocytopenic purpura complicated by polymyositis.

BACKGROUND Cotton wool spots are known to be a complication in patients with thrombotic thrombocytopenic purpura or with polymyositis. CASE A 53-year-old woman developed numerous cotton wool spots around the optic disc of both eyes. OBSERVATIONS Fluorescein angiography disclosed capillary obstruction and microaneurysms in the early phase, followed by dye leakage in the late phase. Systemica...

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Acquired Thrombotic Thrombocytopenic Purpura in a Patient with Pernicious Anemia

Introduction. Acquired thrombotic thrombocytopenic purpura (TTP) has been associated with different autoimmune disorders. However, its association with pernicious anemia is rarely reported. Case Report. A 46-year-old male presented with blood in sputum and urine for one day. The vitals were stable. The physical examination was significant for icterus. Lab tests' results revealed leukocytosis, m...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 2007

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.22477